Key Takeaways
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Menstrual cramps are caused by prostaglandin-driven inflammation and muscle contractions.
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CBD helps reduce inflammation, stress, and pain perception.
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CBG supports muscle relaxation, pain management, mood balance, and sleep regulation.
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Together, CBD + CBG may provide natural, plant-based menstrual relief.
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My Pain Center offers two gummy options for menstrual support—CBD + CBG Gummies and THC + CBD + CBG Relief Gummies.
What Makes Menstrual Pain So Difficult?
For many women and people who menstruate, monthly cramps are more than just a minor inconvenience. They can feel like sharp stabbing pains in the lower abdomen, heavy pressure in the back, or even radiating aches down the legs. For some, the discomfort is so severe that it interferes with work, school, and daily life.
Menstrual pain, also called dysmenorrhea, happens when the uterine lining sheds during a period. This process releases compounds called prostaglandins, which trigger muscle contractions and inflammation. High levels of prostaglandins are linked to stronger, more painful cramps.
While over-the-counter medications like ibuprofen can provide relief, not everyone finds them effective. Plus, frequent use of NSAIDs may cause stomach upset or long-term health concerns. This has led many women to search for natural alternatives.
That is where CBD (cannabidiol) and CBG (cannabigerol) enter the conversation. Both are non-intoxicating cannabinoids from the hemp plant that work with the body’s endocannabinoid system (ECS) to restore balance.
How Menstrual Pain Affects Daily Life
Menstrual pain is not just a physical experience. It affects every part of daily living. A survey by the American College of Obstetricians and Gynecologists found that nearly one in five women misses school or work due to cramps. Others push through, but at the cost of energy, focus, and mood.
The impact shows up in many ways:
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At work or school: Concentration drops, productivity slows, and sitting for long periods can feel unbearable.
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At home: Fatigue and irritability may cause tension in relationships or missed family time.
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In social life: Some people cancel plans or avoid activities they enjoy.
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For sleep: Pain often disrupts rest, creating a cycle of exhaustion and increased discomfort.
This burden is why women are increasingly turning to plant-based, natural solutions like CBD and CBG, hoping for relief that supports their lifestyle without harsh side effects.

Why Traditional Pain Relief Isn’t Always Enough
Most people reach for ibuprofen, naproxen, or acetaminophen when cramps hit. These medications can reduce pain, but they have limitations.
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They wear off quickly, often requiring multiple doses in a single day.
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They may cause stomach irritation when used frequently.
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They don’t always help mood, bloating, or sleep problems.
Hormonal birth control is another option some doctors recommend. It can help reduce the severity of cramps, but it may not be suitable for everyone. Side effects may include weight changes, mood swings, or headaches.
This is where CBD and CBG stand out. They target not just pain, but also inflammation, mood, sleep, and stress, offering a more well-rounded approach to menstrual wellness.
How CBD and CBG Work Together
The ECS is akin to the body’s “control hub” for maintaining balance. It regulates pain, inflammation, mood, stress response, and sleep. When the ECS is supported with cannabinoids like CBD and CBG, it may help restore a calmer internal state.
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CBD is best known for its calming, anti-inflammatory, and pain-modulating effects.
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CBG is often referred to as the “mother cannabinoid” and has demonstrated unique potential for muscle relaxation, pain modulation, and digestive comfort.
When combined, CBD and CBG may offer more substantial relief than either one alone. Scientists refer to this phenomenon as the entourage effect, where multiple cannabinoids work together to achieve a greater impact.
How CBG May Relieve Menstrual Pain
1. Calms Inflammation
During menstruation, prostaglandins cause inflammation in the uterine lining, which leads to cramping. Studies suggest that CBG interacts with COX-2 enzymes involved in the inflammatory cascade. By calming this process, CBG may help reduce the intensity of cramps.
2. Lowers Pain Signals
CBG interacts with TRP (transient receptor potential) channels, the same receptors that detect signals of heat, pressure, and discomfort, which are responsible for pain sensation. By calming these receptors, CBG may “quiet” the nervous system’s pain response, leading to gentler aches.
3. Relaxes Muscle Spasms
Cramping occurs when the uterus undergoes strong muscle contractions. CBG may help relax smooth muscle tissue, which could make contractions less forceful and less painful.
4. Eases Stress and Mood Swings
Hormonal shifts during PMS can trigger irritability, mood swings, or heightened stress. CBG may support GABA activity, a neurotransmitter that promotes calmness in the brain. By boosting GABA signaling, CBG can promote relaxation and reduce emotional tension.
5. Supports Better Sleep
Menstrual pain often disrupts sleep, leaving you exhausted. Poor rest, in turn, exacerbates pain. CBG has balancing effects on circadian rhythms and mood, promoting more restful and deeper sleep.

The Role of CBD in Menstrual Relief
While CBG offers unique muscle and pain benefits, CBD is equally important for menstrual support.
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Reduces inflammation: CBD helps calm prostaglandin activity, thereby lowering uterine inflammation.
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Enhances relaxation: By working with serotonin receptors, CBD improves mood stability and stress resilience.
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Pain perception: CBD interacts with pain pathways in the brain, reducing the intensity of pain perception.
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Hormone balance: Early research suggests CBD may indirectly influence hormone regulation through the ECS, giving some women a sense of greater monthly balance.
Other PMS Symptoms CBD + CBG May Help With
Menstrual cramps are the most talked-about symptom, but PMS brings much more. CBD + CBG may help with:
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Bloating and digestion: Both cannabinoids have a soothing effect on the digestive system, which may help reduce bloating.
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Breast tenderness: Anti-inflammatory properties may calm swelling and sensitivity.
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Headaches: Cannabinoids can ease tension and calm overactive pain receptors.
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Mood swings and anxiety: By regulating serotonin and GABA, they promote calm and emotional steadiness.
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Fatigue: By improving sleep, CBD and CBG may help reduce the exhaustion that often accompanies a cycle.
The Science of the Endocannabinoid System and Periods
The ECS plays a central role in menstrual health. It helps regulate:
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Uterine muscle contractions: Too much prostaglandin = painful cramps. The ECS can help calm this response.
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Hormone signaling: The ECS works with estrogen and progesterone pathways, which affect PMS symptoms.
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Pain perception: The ECS interacts with opioid and TRP receptors, controlling how pain is experienced.
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Mood and stress: Endocannabinoids, such as anandamide, naturally lift mood. Low levels are associated with PMS-related irritability.
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Sleep-wake cycle: ECS balance helps maintain steady circadian rhythms.
When CBD and CBG supplement the ECS, they help restore balance in these areas, making periods more manageable.
Real-Life Benefits: What Women Report
Many women share personal experiences of using CBD + CBG gummies for menstrual relief. Reports often include:
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Shorter duration of cramps
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More manageable pain without relying only on painkillers
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Less bloating and abdominal tightness
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Calmer mood during PMS
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Easier time falling asleep despite discomfort
While not every woman notices the same results, the growing number of positive stories suggests CBD and CBG are a promising option.
How to Choose the Right CBD + CBG Product
When shopping for menstrual relief products, look for:
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Third-party lab testing to confirm purity and potency
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Clear labeling on CBD and CBG content per serving
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Gummies vs. oils vs. creams, depending on preference
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Optional THC if you want more substantial pain relief
This ensures you get a product that is safe, effective, and trustworthy.
Product Spotlight: CBD + CBG Gummies
CBD + CBG Gummies
These gummies combine 25mg of CBD and 25mg of CBG for everyday balance and well-being. They are THC-free, making them an excellent choice for women who want menstrual support without psychoactive effects, perfect for easing inflammation, calming mood swings, and supporting restful sleep.
THC + CBD + CBG Relief Gummies – Blood Orange
For those who want more substantial relief, these gummies add a touch of Delta-9 THC. THC enhances pain relief and relaxation, especially for women with severe cramps. The blood orange flavor makes them a tasty way to manage monthly discomfort naturally.
Lifestyle Tips to Pair With CBD + CBG
Cannabinoids work best when combined with supportive habits:
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Apply a heating pad to the lower abdomen
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Drink warm teas, such as ginger or chamomile.
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Do gentle yoga stretches for the pelvis and lower back?
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Eat magnesium-rich food, such as leafy greens, nuts, and seeds.
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Prioritize hydration to reduce bloating.
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Practice deep breathing or meditation to calm stress.s
These lifestyle shifts enhance the benefits of CBD + CBG and make cramps easier to manage.

Legal and Safety Considerations
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Legality: Hemp-derived CBD and CBG products with less than 0.3% THC are federally legal in the U.S. Always check local state laws.
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Safety: CBD and CBG are generally well tolerated. Mild side effects may include drowsiness or dry mouth.
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Interactions: If you take prescription medications, consult a doctor before adding cannabinoids.
CBD vs. CBG vs. THC Blends
Formula |
Best For |
Psychoactive? |
Example Product |
CBD only |
Stress, mood, mild cramps |
No |
CBD oils, gummies |
CBG only |
Muscle relaxation, digestive comfort |
No |
CBG oils, gummies |
CBD + CBG |
Full-spectrum PMS relief, inflammation + pain |
No |
|
THC + CBD + CBG |
Severe cramps, deeper relaxation, sleep |
Yes |
Science and Research on CBD + CBG for Pain
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A study in Frontiers in Pharmacology found that cannabinoids can calm inflammation and interact with TRP pain receptors.
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Research in the European Journal of Pharmacology suggests that CBG may reduce muscle contractions, which could be beneficial for uterine cramps.
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CBD has been widely studied for pain modulation and mood regulation, with promising results in chronic pain conditions.
While more studies are needed specifically on menstrual pain, early findings and real-world reports are encouraging.
FAQs
Can CBD and CBG really help with period cramps?
Yes, studies suggest they calm inflammation, ease muscle contractions, and reduce pain signals. Many women also report personal relief.
Do you need THC for menstrual relief?
Not necessarily. CBD + CBG alone can be very effective. But if cramps are severe, a low dose of THC may add extra pain relief.
When should I take CBD + CBG for my cycle?
Start a day or two before your period and continue throughout your cycle for best results.
Will CBD or CBG make me high?
No. Both CBD and CBG are non-intoxicating. Only products with THC may cause a high.
Are CBD and CBG safe for long-term use?
Yes, they are generally considered safe. Always choose products that have been third-party tested to ensure purity.